EFFICACY AND SAFETY OF PD-1 INHIBITORS MONOTHERAPY FOR ELDERLY PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER

Efficacy and Safety of PD-1 Inhibitors Monotherapy for Elderly Patients with Advanced Non-small Cell Lung Cancer

Background Immunotherapy represented by programmed death protein-1 (PD-1) inhibitors has gradually become the standard treatment of advanced non-small cell lung cancer (NSCLC) in recent years, changing the treatment landscape of advanced NSCLC.However, most PD-1-related studies excluded patients with NSCLC more than 70 or 75 years, resulting in rel

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Addressing the need for rapid treatment of agitation in schizophrenia and bipolar disorder: focus on inhaled loxapine as an alternative to injectable agents

Leslie CitromeDepartment of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, USAAbstract: Agitation (excessive motor or verbal activity) can be associated with schizophrenia or bipolar mania, and can further escalate into aggressive behavior and potentially lead to injuries in patients and staff.Medications used to treat

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The Differential Antagonistic Ability of Curcumin against Cytotoxicity and Genotoxicity Induced by Distinct Heavy Metals

Widespread heavy metal pollution has aroused severe health risks worldwide.Curcumin has been reported to play a wide-spectrum protective role for various heavy metals.However, the specificity and difference in the antagonistic ability of curcumin against distinct types of heavy metals are still largely unknown.Here, using cadmium (Cd), arsenic (As)

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